Article Cardiac & Cardiovascular Systems
Incident Heart Failure in Patients With Coronary Artery Disease Undergoing Percutaneous Coronary Intervention
Jun Gu, Zhao-fang Yin, Zuo-jun Xu, Yu-qi Fan, Chang-qian Wang, Jun-feng Zhang
Summary: This study showed that after PCI, the predominant subtype of HF is HFpEF, and higher BNP levels, lower eGFR levels, and atrial fibrillation are independent risk factors for new-onset HF. Being male and being prescribed with ACEI/ARB medications are negative predictors for new-onset HF. Additionally, long-term ACEI/ARB therapy is associated with reduced risks of developing all three subtypes of HF (HFrEF, HFmrEF, and HFpEF), compared to beta-blocker use.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)
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Article Cardiac & Cardiovascular Systems
Evolution, coronary artery bypass surgery and outcomes of right ventricular dysfunction in ischaemic cardiomyopathy
Zhuoming Zhou, Bohao Jian, Guangguo Fu, Haoliang Liu, Yang Huang, Zicong Feng, Suiqing Huang, Huayang Li, Mengya Liang, Zhongkai Wu
Summary: This study investigated the impact of right ventricular dysfunction (RVD) on prognosis and treatment choice in patients with ischaemic cardiomyopathy (ICM). The results showed that RVD was associated with a worse prognosis in patients with ICM and that CABG provided no additional survival benefits to patients with moderate-to-severe RVD. The evolution of RV function had important prognostic implications and emphasized the importance of both pre- and post-therapeutic RV assessment.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2023)
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Article Cardiac & Cardiovascular Systems
Effect of Heart Failure on Long-Term Clinical Outcomes After Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Severe Coronary Artery Disease
Ko Yamamoto, Yukiko Matsumura-Nakano, Hiroki Shiomi, Masahiro Natsuaki, Takeshi Morimoto, Kazushige Kadota, Tomohisa Tada, Yasuaki Takeji, Yusuke Yoshikawa, Kazuaki Imada, Takenori Domei, Kazuhisa Kaneda, Ryoji Taniguchi, Natsuhiko Ehara, Ryuzo Nawada, Kyohei Yamaji, Eri Kato, Mamoru Toyof*cku, Naoki Kanemitsu, Eiji Shinoda, Satoru Suwa, Atsushi Iwakura, Toshihiro Tamura, Yoshiharu Soga, Tsukasa Inada, Mitsuo Matsuda, Tadaaki Koyama, Takeshi Aoyama, Yukihito Sato, Yutaka Furukawa, Kenji Ando, Fumio Yamazaki, Tatsuhiko Komiya, Kenji Minatoya, Yoshihisa Nakagawa, Takeshi Kimura
Summary: This study found a significant interaction between heart failure and the mortality risk of PCI relative to CABG, with higher mortality risk in patients with heart failure and neutral risk in patients without heart failure.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2021)
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Article Cardiac & Cardiovascular Systems
Low coronary flow relative to myocardial mass predicts heart failure in symptomatic hypertensive patients with no obstructive coronary artery disease
Jenifer M. Brown, Wunan Zhou, Brittany Weber, Sanjay Divakaran, Leanne Barrett, Courtney F. Bibbo, Jon Hainer, Viviany R. Taqueti, Sharmila Dorbala, Ron Blankstein, Marcelo F. Di Carli
Summary: Insufficient myocardial perfusion to match global metabolic demand may be a risk marker for heart failure.
EUROPEAN HEART JOURNAL (2022)
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Article Cardiac & Cardiovascular Systems
Long-term mortality in patients with ischaemic heart failure revascularized with coronary artery bypass grafting or percutaneous coronary intervention: insights from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR)
Sebastian Volz, Bjorn Redfors, Oskar Angeras, Dan Ioanes, Jacob Odenstedt, Sasha Koul, Inger Valeljung, Christian Dworeck, Robin Hofmann, Emma Hansson, Dimitrios Venetsanos, Anders Ulvenstam, Tomas Jernberg, Truls Ramunddal, Petur Petursson, Ole Frobert, David Erlinge, Anders Jeppsson, Elmir Omerovic
Summary: In patients with heart failure due to ischaemic heart disease, coronary artery bypass grafting (CABG) was associated with greater long-term survival compared to percutaneous coronary intervention (PCI). The risk of death was lower after CABG, and increased linearly with quintiles of hospitals where PCI was the preferred revascularization method.
EUROPEAN HEART JOURNAL (2021)
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Article Cardiac & Cardiovascular Systems
Case report: Heart failure secondary to myocardial infarction in a fertile woman with woven coronary artery
Jiayi Hu, Qian Wang, Mei Dong, Huixia Lu
Summary: This case report emphasizes the importance of potential causes in cardiovascular events occurring in fertile women.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)
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Review Biochemistry & Molecular Biology
Coronary Artery Spasm-Related Heart Failure Syndrome: Literature Review
Ming-Jui Hung, Chi-Tai Yeh, Nicholas G. Kounis, Ioanna Koniari, Patrick Hu, Ming-Yow Hung
Summary: Although heart failure can worsen over time, some cases can be reversed with appropriate treatments. Coronary artery spasm is becoming the most frequent cause of heart failure worldwide, but it is often under appreciated and misdiagnosed. It can lead to various complications such as syncope, arrhythmias, and myocardial ischemic syndromes. Prompt diagnosis and treatment are important to prevent these complications. This review focuses on the epidemiology, clinical features, pathophysiology, and management of patients with coronary artery spasm-related heart failure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
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Article Clinical Neurology
Sleep apnea and recurrent heart failure hospitalizations after coronary artery bypass grafting
Yao Hao Teo, Wilson W. Tam, Chieh-Yang Koo, Aye-Thandar Aung, Ching-Hui Sia, Raymond C. C. Wong, William Kong, Kian-Keong Poh, Theodoros Kofidis, Pipin Kojodjojo, Chi-Hang Lee
Summary: The study found that sleep apnea was associated with recurrent heart failure hospitalizations, with repeat events accounting for two-thirds of heart failure hospitalizations in patients after CABG.
JOURNAL OF CLINICAL SLEEP MEDICINE (2021)
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Review Cardiac & Cardiovascular Systems
Hybrid coronary revascularization versus coronary artery bypass grafting for multivessel coronary artery disease: A systematic review and meta-analysis
Lauren Kari Dixon, Umme Akberali, Ettorino Di Tommaso, Sarah J. George, Thomas W. Johnson, Vito Domenico Bruno
Summary: Compared with coronary artery bypass grafting (CABG), hybrid coronary revascularization (HCR) has a slightly higher short-term mortality but the difference is not significant in patients with multi-vessel coronary artery disease (MCAD). Similar rates of mid-term survival and other short-term post-operative complications were found between the two groups. HCR has shorter intensive care unit stays and reduced requirement for blood transfusion.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2022)
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Article Cardiac & Cardiovascular Systems
Outcomes of coronary artery bypass grafting in patients with heart failure with a midrange ejection fraction
Salil Deo, Varun Sundaram, Jayakumar Sahadevan, Padmini Selvaganesan, Srikrishna Madan Mohan, Joseph Rubelowsky, Richard Josephson, Yakov Elgudin, Ahmet Kilic, Brian Cmolik
Summary: Coronary artery bypass grafting (CABG) improves survival in heart failure patients with severely reduced left ventricular systolic function (LVEF). However, little is known about adverse cardiovascular events after CABG in patients with heart failure with midrange ejection fraction (HFmrEF; LVEF > 40% and < 55%). In this study, data from the Veterans Affairs national database were analyzed to compare mortality and heart failure hospitalization rates among different patient groups.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2023)
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Article Cardiac & Cardiovascular Systems
Epicardial Transplantation of Autologous Cardiac Micrografts During Coronary Artery Bypass Surgery
Annu Nummi, Severi Mulari, Juhani A. Stewart, Sari Kivisto, Kari Teittinen, Tuomo Nieminen, Milla Lampinen, Tommi Patila, Harri Sintonen, Tatu Juvonen, Markku Kupari, Raili Suojaranta, Esko Kankuri, Ari Harjula, Antti Vento
Summary: The epicardial transplantation of atrial appendage micrografts during CABG surgery was shown to be safe and feasible, resulting in an increase in viable cardiac tissue at the infarct site. This approach demonstrated initial therapeutic effects on the myocardium and has the potential to serve as a delivery platform for cardiac gene therapies.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)
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Article Endocrinology & Metabolism
Sex differences following percutaneous coronary intervention or coronary artery bypass surgery for acute myocardial infarction
Donna Shu-Han Lin, Yu-Sheng Lin, Jen-Kuang Lee, Hsien-Li Kao
Summary: This study compares the outcomes of women and men with acute myocardial infarction (AMI) who underwent percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG). It found that women had worse in-hospital and long-term outcomes, especially in the PCI group. Women who underwent PCI were more likely to be admitted for heart failure during follow-up.
BIOLOGY OF SEX DIFFERENCES (2022)
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Article Medicine, General & Internal
Joint effect of heart failure and coronary artery disease on the risk of death during hospitalization for COVID-19
Fabio Angeli, Jacopo Marazzato, Paolo Verdecchia, Antonella Balestrino, Claudio Bruschi, Piero Ceriana, Luca Chiovato, Laura Adelaide Dalla Vecchia, Roberto De Ponti, Francesco Fanfulla, Maria Teresa La Rovere, Francesca Perego, Simonetta Scalvini, Antonio Spanevello, Egidio Traversi, Dina Visca, Michele Vitacca, Tiziana Bachetti
Summary: The combination of heart failure and coronary artery disease significantly increases the risk of death in patients with COVID-19, with a synergistic effect observed when the two conditions are present together. This impact on mortality is independent of other adverse prognostic markers.
EUROPEAN JOURNAL OF INTERNAL MEDICINE (2021)
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Article Medicine, General & Internal
Coronary Artery Bypass Graft Surgery Brings Better Benefits to Heart Failure Hospitalization for Patients with Severe Coronary Artery Disease and Reduced Ejection Fraction
Yu-Wen Chen, Wei-Chieh Lee, Hsiu-Yu Fang, Cheuk-Kwan Sun, Jiunn-Jye Sheu
Summary: This study compared the outcomes of percutaneous coronary intervention (PCI) and coronary artery bypass graft surgery (CABG) for revascularization in patients with reduced ejection fraction (EF) and severe coronary artery disease (CAD). The results showed that compared to PCI, CABG was associated with a lower incidence of heart failure (HF) hospitalization but worse survival outcomes.
DIAGNOSTICS (2022)
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Article Medicine, General & Internal
Selected Transesophageal Echocardiographic Parameters of Left Ventricular Diastolic Function Predict Length of Stay Following Coronary Artery Bypass Graft-A Prospective Observational Study
Samhati Mondal, Nauder Faraday, Wei Dong Gao, Sarabdeep Singh, Sachidanand Hebbar, Kimberly N. Hollander, Thomas S. Metkus, Lee A. Goeddel, Maria Bauer, Brian Bush, Brian Cho, Stephanie Cha, Stephanie O. Ibekwe, Domagoj Mladinov, Noah S. Rolleri, Laeben Lester, Jochen Steppan, Rosanne Sheinberg, Nadia B. Hensley, Anubhav Kapoor, Jeffrey M. Dodd-O
Summary: In patients undergoing coronary artery bypass surgery, diastolic dysfunction based on selected transesophageal echocardiography parameters is associated with prolonged duration of postoperative hospital stay.
JOURNAL OF CLINICAL MEDICINE (2022)
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Article Cardiac & Cardiovascular Systems
Cardiovascular evaluation of pregnant women with hypertrophic cardiomyopathy
Ahmet Guner, Ozkan Candan, Serkan Kahraman, Ezgi Gultekin Guner, Sevgi Ozcan, Mustafa Ozan Gursoy, Macit Kalcik, Abdulkadir Uslu, Esra Donmez, Regayip Zehir, Mehmet Erturk, Mustafa Yildiz, Mehmet Ozkan
Summary: This study retrospectively reviewed the outcomes of pregnant women with HCM and identified HF and high left ventricular outflow tract gradient as important risk factors for the development of cardiac complications.
HERZ (2023)
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Article Cardiac & Cardiovascular Systems
Can GRACE Risk Score Predict Mortality and the Need for Thrombolytic Treatment in Acute Pulmonary Embolism?
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Murat Ziyrek, Ertugrul Okuyan
Summary: This study aimed to evaluate the predictive value of the GRACE risk score in acute pulmonary embolism (PE) patients for 30-day mortality and the need for thrombolytic treatment. The study found that the GRACE risk score, along with the PESI score, were independent risk factors associated with 30-day mortality and the need for thrombolytic treatment. The GRACE risk score showed high sensitivity and specificity in predicting mortality, and its combination with the PESI score helped define high-risk PE patients and predict poor prognosis.
AMERICAN JOURNAL OF CARDIOLOGY (2024)
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Article Hematology
Is dynamic change in mean platelet volume related with composite endpoint development after transcatheter aortic valve replacement?
Orhan Ince, Kamil Gulsen, Sevgi Ozcan, Esra Donmez, Murat Ziyrek, Irfan Sahin, Ertugrul Okuyan
Summary: Aortic valve stenosis is the most common valvular disease, and surgical or transcatheter aortic valve replacement is the treatment options. In this study, the researchers found that the increase in MPV after TAVR may be an indicator of adverse outcomes within 1 month.
BLOOD COAGULATION & FIBRINOLYSIS (2023)
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Article Medical Laboratory Technology
The association between hemogram parameters and the development of contrast-induced nephropathy in patients presenting with non-ST-elevation myocardial infarction
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Ertugrul Okuyan
Summary: This study aimed to investigate the role of hemogram parameters in predicting the development of contrast-induced nephropathy (CIN) in patients with non-ST segment elevation myocardial infarction (non-STEMI) treated with percutaneous coronary intervention (PCI). The results showed that age, diabetes, congestive heart failure, volume of contrast medium, mean platelet volume (MPV), and neutrophil/lymphocyte ratio (NLr) were independent risk factors associated with CIN development. Additionally, MPV and NLr were demonstrated as predictors of CIN development in non-STEMI patients treated with PCI.
ADVANCES IN LABORATORY MEDICINE-AVANCES EN MEDICINA DE LABORATORIO (2023)
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Article Cardiac & Cardiovascular Systems
What Is the Impact of Liver Function to Predict Mortality in Patients with Severe Aortic Stenosis and Reduced Ejection Fraction?
Sevgi Ozcan, Esra Donmez, Irfan Sahin, Ertugrul Okuyan
Summary: This study evaluated the prognostic impact of liver function reserve on 30-day and 1-year mortality and rehospitalization in patients with severe symptomatic aortic stenosis undergoing transcatheter aortic valve implantation. The high albumin-bilirubin score was found to be significantly associated with increased mortality and worse overall outcomes.
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY (2023)
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Article Cardiac & Cardiovascular Systems
Predictive Value of CHA2DS2 -VASc Score in Patients with Contrast-Induced Nephropathy After Primary Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction
Esra Doenmez, Sevgi Ozcan, Orhan Ince, Irfan Sahin, Ertugrul Okuyan
Summary: This study evaluated the CHA2DS2-VASc score as a surrogate for contrast-induced nephropathy and its relationship with major adverse cardiac events during hospitalization. The study found that age, diabetes, history of stroke, volume of contrast medium, left ventricular ejection fraction, and CHA2DS2-VASc score were associated with contrast-induced nephropathy development. A CHA2DS2-VASc score of >=2.5 was associated with high sensitivity and specificity in predicting contrast-induced nephropathy development.
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY (2023)
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Article Cardiac & Cardiovascular Systems
Modified Glasgow Prognostic Score May Be Useful to Predict Major Adverse Cardiac Events in Heart Failure Patients Undergone Cardiac Resynchronization Treatment
Guney Erdogan, Mustafa Yenercag, Melisa Ucar, Onur Ozturk, Onur Osman Seker, Osman Can Yontar, Ender Ozgun Cakmak, Ali Karagoz, Irfan Sahin, Ugur Arslan
Summary: This study investigated the association of modified Glasgow prognostic score with death and hospitalization in cardiac resynchronization therapy with defibrillation patients. The modified Glasgow prognostic score was found to be a predictor of long-term heart failure hospitalization and death, along with age and left atrial diameter.
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY (2023)
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Article Pharmacology & Pharmacy
Correlation between the serum lumican level and the severity of coronary artery disease
A. Kirankaya, S. Tugrul, S. Ozcan, O. Ince, E. Donmez, A. Atici, E. Hancioglu, E. Okuyan, I. Sahin
Summary: This study aimed to investigate the relationship between circulating lumican levels and the severity of coronary artery disease (CAD). The results showed that lumican levels were higher in the advanced CAD group and positively correlated with the Gensini score. Diabetes mellitus, EF, and lumican were found to be predictive factors for advanced CAD. Lumican levels can be used to predict the seriousness of CAD with a sensitivity rate of 64% and specificity rate of 65%.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES (2023)
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